ISSN 1662-4009 (online)

ey0018.10-12 | (1) | ESPEYB18

10.12. Cognitive function following diabetic ketoacidosis in children with new-onset or previously diagnosed type 1 diabetes

S Ghetti , N Kuppermann , A Rewers , SR Myers , JE Schunk , MJ Stoner , A Garro , KS Quayle , KM Brown , JL Trainor , L Tzimenatos , AD De Piero , JK McManemy , LE Nigrovic , MY Kwok , CS 3rd Perry , CS Olsen , TC Casper , NS; Pediatric emergency care applied research network (PECARN) DKA FLUID study group Glaser

Diabetes Care. 2020;43(11):2768–2775. doi: 10.2337/dc20-0187.In this observational analysis of a patient cohort, a single diabetic ketoacidosis (DKA) episode was associated with lower cognition and memory both in children with newly diagnosed T1D and in children with known T1D.Children (N=758) were 6-18 years old, taking part in a multisite randomized trial e...

ey0016.10-6 | (1) | ESPEYB16

10.6. Clinical trial of fluid infusion rates for pediatric diabetic ketoacidosis

N Kuppermann , S Ghetti , JE Schunk , MJ Stoner , A Rewers , JK McManemy , SR Myers , LE Nigrovic , A Garro , KM Brown , KS Quayle , JL Trainor , L Tzimenatos , JE Bennett , AD DePiero , MY Kwok , CS 3rd Perry , CS Olsen , TC Casper , JM Dean , NS Glaser , DKA FLUID Study Group PECARN

To read the full abstract: N Engl J Med. 2018 Jun 14;378(24):2275–2287Neurological complications of diabetic ketoacidosis (DKA) are still causes of significant mortality and morbidity in type 1 diabetes (T1D). Children are still being reported with acute cerebral infarction (CI) and extra pontine myelinolysis (EPM) at onset of T1D (1). Frequently, their clinical management had not b...